Coffee boosts memory, relieves stress: Study

by L&D02 Sep 2016
Drinking coffee (in moderation) has been linked with burning fat, fighting depression and even lowering your risk of Type II diabetes and Parkinson’s.
Now, new research suggests that the caffeine in coffee helps boost your memory and reduce stress.
The study looked at the receptor in the brain which wears down with age and stress.
The researchers have confirmed that this certain receptor, called adenosine A2AR, is linked to memory impairments related to age.
As time goes by, our brains increase the amount of stress hormones which has a harmful impact on memory.

Researchers at the French research institute Inserm induced this ageing process on animal models.

They then fed them the caffeine analog, which blocks and protect the age- and stress-related receptor. Consequently, their memory and stress normalised.

This study is set to be used to further develop their understanding of cognitive impairments in conditions such as Alzheimer's.
Luisa Lopes, coordinator of the study, said this is part of a larger study initiated four years ago in which they identified the role of this receptor in stress, but did not know whether its activation would be enough to trigger all the changes.
“We now found that by altering the amount of this receptor alone in neurons from hippocampus and cortex – memory related areas – is sufficient to induce a profile that we designate as ‘early-aging’ combining the memory loss and an increase in stress hormones in plasma (cortisol),” Lopes was quoted as saying by Consumer Affairs.
“This is important not only to understand the fundamental changes that occur upon aging, but it also identifies the dysfunctions of the adenosine A2AR receptor as a key player in triggering these changes. And a very appealing therapeutic target.”
The researcher director David Blum added that in elderly people, we know there is an increase of stress hormones that have an impact on memory.
“Our work supports the view that the precognitive effects of A2AR antagonists, namely caffeine, observed in Alzheimer’s and age-related cognitive impairments may rely on this ability to counteract the loss of stress controlling mechanisms that occurs upon aging,” said Blum.